Dysplastic nevus
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Dysplastic nevi ― Biopsy e buelloa ho batho ba Bophirimela.
References
Dysplastic nevus , e tsejoang hape e le atypical kapa Clarks nevus, e tsositse likhang ho dermatology le dermatopathology. Hangata lingaka li hlahloba li-moles tsena hobane li ka shebahala li sa tloaeleha 'me li hlahisa matšoenyeho ka melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , e tsejoang hape e le atypical kapa Clark nevi, ka linako tse ling e ka lebisa ho melanoma. Hoo e ka bang 36% ea melanoma e fumanoa haufi le dysplastic nevi. Matšoao a hore dysplastic nevus e ka fetoha melanoma a kenyelletsa sebopeho se sa lekaneng, liphetoho tse ngata tsa 'mala kapa' mala o moputsoa. Hangata mafu ana a kankere a hlaha a sa le monyenyane (hoo e ka bang bohareng ba lilemo tse mashome a mararo) , a ka ba a mangata, 'me a atisa ho ba kutu. Ka liphatsa tsa lefutso, dysplastic nevi li lipakeng tsa benign nevi le melanoma. Leha ho le joalo, ke 20% ho isa ho 30% feela ea melanoma e tsoang ho nevi e teng. Kaha li-nevi tse ngata ha li fetohe melanoma, hangata ha ho khothalletsoe ho li tlosa ka mokhoa o thibelang.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma ke mofuta oa hlahala e hlahang ha melanocyte, lisele tse ikarabellang bakeng sa 'mala oa letlalo, li fetoha mofetše. Melanocyte e tsoa ho neural crest. Sena se bolela hore melanoma e ka hlaha eseng letlalong feela empa le libakeng tse ling moo lisele tsa neural crest li falla, joalo ka lesela la mala le boko. Sekhahla sa ho pholoha ha bakuli ba nang le melanoma ea pele-pele (mohato oa 0) se phahame ho 97%, ha se theoha haholo hoo e ka bang 10% ho ba fumanoeng ba e-na le lefu le tsoetseng pele (mokhahlelo oa IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Mofetše kotsi
Joalokaha ho bonoa ho batho ba Caucasia ba United States, ba nang le dysplastic nevi ba na le kotsing ea bophelo bohle ba ho ba le melanoma e fetang 10%. Ka lehlakoreng le leng, ba se nang dysplastic nevus ba kotsing ea ho ba le melanoma e ka tlase ho 1%.
○ Precaution bakeng sa batho ba nang le dysplastic nevi
Hangata ho khothaletsoa ho itlhahloba letlalo bakeng sa ho thibela melanoma (ka ho khetholla nevi e sa tloaelehang e ka tlosoang) kapa bakeng sa ho lemoha kapele lihlahala tse teng. Batho ba nang le nalane ea botho kapa ea lelapa ea mofets'e oa letlalo kapa oa li-multiple atypical nevi ba lokela ho bona ngaka ea dermatologist bonyane hang ka selemo ho netefatsa hore ha ba hlahise melanoma.
Kgutsufatso [ABCDE] e bile molemo bakeng sa ho thusa bafani ba tsa bophelo bo botle le batho ba ikemetseng ho hopola litšobotsi tsa mantlha tsa melanoma. Ka bomalimabe ho motho ea tloaelehileng, keratose tse ngata tsa seborrheic, lentigo senilis tse ling, esita le li-warts li ka ba le litšobotsi tsa [ABCDE], 'me li ke ke tsa khetholloa ho melanoma.
○ [ABCDE]
Asymmetrical: Leqeba la letlalo la asymmetrical.
Border: Moeli oa leqeba ha o tloaelehe.
Color: Hangata melanoma e na le mebala e mengata e sa tloaelehang.
Diameter: Nevi e kholo ho feta 6 mm e na le monyetla oa ho ba melanoma ho feta nevi e nyane.
Evolution: Phetoho (ke hore phetoho) ea nevus kapa leqeba e ka bontša hore leqeba le ntse le mpefala.